Researchers Make Strides in Study of Cat Heart Disease

A team funded by the Winn Feline Foundation identifies a gene mutation that may be linked to feline hypertrophic cardiomyopathy in Ragdoll cats.

Posted: June 13, 2007 5 a.m. EST

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The genal mutation that causes hypertrophic cardiomyopathy was found in the Ragdoll family of cats
Researchers have found a mutated gene that is linked to hypertrophic cardiomyopathy in Ragdoll cats. 
Researchers funded by the Winn Feline Foundation have identified a new mutation in a myosin binding protein C gene that is associated with hypertrophic cardiomyopathy in Ragdoll cats, the foundation reported. The research team, led by Kathryn M. Meurs of Washington State University and assisted by others at the University of California at Davis, has determined that the mutation changes a conserved amino acid and therefore appears to alter the protein’s structure produced by the gene.

In an earlier study, the same research team identified a mutation in the same gene in Maine Coon cats. The mutation found in this study was located in a different area of the affected gene, and was found in Ragdoll cats, a breed unrelated to the Maine Coon. These separate findings suggest that the mutations occurred independently and were not inherited from a common ancestor, the foundation reported.

Hypertrophic cardiomyopathy is the most common heart disease found in cats, and can affect non-pedigreed cats as well as some pedigreed breeds. These latest studies may lead to improved testing and pave the way toward creating new drug therapies, the foundation reported.

For more information about the Winn Feline Foundation, click here

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Reader Comments

Veronica    Jacksonville, FL

2/12/2013 3:10:37 PM

The doctor thought my Ragdoll cat billy had a heart murmur, but we watched it and a couple of months later she was cleared with no heart mur mur. Thank goodness!!

Christina    Chicago, IL

12/4/2008 8:02:56 PM

This really helped me on a school project. It's realy help full for reseach like this to be in the open so people like me can find it Thankyou.... =0

statia    Edmonton, AL

6/14/2007 12:30:54 AM

glad to hear they are making strides in the reserch

Samantha    Edmonton, AL

6/14/2007 12:19:53 AM

this is great lets continue the reserch

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